KCA is currently running two research projects aimed at the transfer of evidence into clinical practice:
Consent, communication and decision making in early phase paediatric cancer trials
The purpose of early phase clinical trials is to evaluate new drugs. Participants in such trials have usually already failed standard treatment and are considered incurable. Early phase trials in children with cancer are ethically controversial, due to the vulnerability of this group of patients and their families. Communication and decision-making in this context pose major challenges for clinicians and parents alike. This project aims to gain a better understanding of clinician, parent and community attitudes, as well as communication and parent decision-making issues when faced with the prospect of enrolling their child in an early phase clinical trial.
Development of a best practice model of care for survivors of paediatric cancer
Survivors of child cancer often live for several decades after they have been cured, during which time they are at risk of late effects of the treatment they received. Despite the importance of ongoing care, less than a third of survivors regularly attend a long term follow up (LTFU) clinic. This project aims to evaluate a range of models of LTFU, from the perspective of both survivors and professionals, and to develop an evidence-based model of best care for survivors.